Journal article
The status and challenges of replicating the mechanical properties of connective tissues using additive manufacturing
Saeed Miramini, Katie L Fegan, Naomi C Green, Daniel M Espino, Lihai Zhang, Lauren EJ Thomas-Seale
Journal of the Mechanical Behavior of Biomedical Materials | Elsevier BV | Published : 2020
Abstract
The ability to fabricate complex structures via precise and heterogeneous deposition of biomaterials makes additive manufacturing (AM) a leading technology in the creation of implants and tissue engineered scaffolds. Connective tissues (CTs) remain attractive targets for manufacturing due to their “simple” tissue compositions that, in theory, are replicable through choice of biomaterial(s) and implant microarchitecture. Nevertheless, characterisation of the mechanical and biological functions of 3D printed constructs with respect to their host tissues is often limited and remains a restriction towards their translation into clinical practice. This review aims to provide an update on the curr..
View full abstractRelated Projects (2)
Grants
Awarded by Australian Research Council
Funding Acknowledgements
The authors would like to thank the University of Melbourne and the University of Birmingham for their support. In addition, authors Saeed Miramini and Lihai Zhang acknowledge funding from the Australian Research Hub for Nanoscience-based Construction Material Manufacturing (ARC IH150100006). Further, author Katie L. Fegan gratefully acknowledges financial support from the EPSRC through a studentship from the Physical Sciences for Health Centre for Doctoral Training (EP/L016346/1). Author N.C. Green received funding from the EPSRC Impact Acceleration Account (EP/R11651/1) in association with the EPSRC project “Challenging the forms of bias in physical science and engineering research” (EP/SO11927/1).